Archives of Head and Neck Surgery
Archives of Head and Neck Surgery
Case Report Miscellaneous

Kimura’s disease

Paola Andrea Galbiatti Pedruzzi, Benedito Valdecir de Oliveira, Jacobson Correia Leite de Britto, Roberta Targa Stramandinoli, Ana Helena Willrich, Juliana Elizabeth Jung

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A 72-years-old man presents with a bilateral mass in the retroauricular region, diagnosed as Kimura disease. Kimura disease is a chronic disorder of unknown origin, common in East Asia but rare in other world regions. The clinical presentation of this disease is the triad of lymphadenopathy in the head and neck, peripheral blood eosinophilia and increased levels of immunoglobulin E. Treatment includes corticosteroids, chemotherapy, radiotherapy, and surgery.


angiolymphoid hyperplasia with eosinophilia; eosinophilia; lymph nodes.


1. Kim HT, Szeto C. Eosinophilic, hyperplastic lymphogranuloma, comparison with Mikulicz’s disease. Chin Med J. 1937;23:699.

2. Kimura T, Yoshimura S, Ishikawa E. Unusual granulation combined with hyperplastic changes of lymphatic tissue. Trans Soc Pathol Jpn. 1948;37:179.

3. Chusid MJ, Rock AL, Sty JR, Oechler HW, Beste DJ. Kimuras disease: an unusual cause of cervical tumour. Arch Dis Child. 1997;77(2):153-4. PMid:9301357.

4. Kung IT, Gibson JB, Bannatyne PM. Kimuras disease: a clinico-pathological study of 21 cases and its distinction from angiolymphoid hyperplasia with eosinophilia. Pathology. 1984;16(1):39-44. PMid:6718071.

5. Urabe A, Tsuneyoshi M, Enjoji M. Epithelioid hemangioma versus Kimura’s disease: a comparative clinicopathologic study. Am J Surg Pathol. 1987;11(10):758-66. PMid:3116865.

6. Kuo T, Shih L-Y, Chan H-L. . Kimura’s disease: involvement of regional lymph nodes and distinction from angiolymphoid hyperplasia with eosinophilia. Am J Surg Pathol. 1988;12(11):843-54. PMid:2461103.

7. Yuen HW, Goh YH, Low WK, Lim-Tan SK. Kimuras disease: a diagnostic and therapeutic challenge. Singapore Med J. 2005;46(4):179-83. PMid:15800724.

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