Archives of Head and Neck Surgery
Archives of Head and Neck Surgery
Original Article Thyroid diseases and tumors

Chronic hypoparathyroidism after thyroid surgery: Benefits of specialized and personalized care in a tertiary public hospital

Marcos Roberto Tavares, Felipe Augusto Brasileiro Vanderlei, Mariana Faccini Teixeira, Daniel Abreu Rocha, Santiago Nuñez Del Arco Serrano, Luis Felipe de Barros Ura, Raquel Ajub Moyses

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Introduction: As the number of thyroid operations increases, the incidence of complications also increases, including transitory and definite hypoparathyroidism. Since each patient presents different and unpredictable symptoms, affecting several organs and systems, they need personalized care. Even when patients presented with low calcium blood levels, the previous results were considered acceptable, usually using oral prescriptions of calcium carbonate and calcitriol. We created in March 2017 a specialized outpatient treatment facility for those patients focused on generating experience and knowledge about hypoparathyroidism. Objective: To analyze the challenges and the impact of specialized care in diagnosis, treatment and in follow-up of patients with postoperative hypoparathyroidism, with potential to improve teaching and further research possibilities in the subject. Methods: 61 patients were studied: 55 women, age 18-55. A retrospective study was performed, considering specialized guidelines. We also analyzed blood levels of calcium, parathyroid hormone, vitamin D, and other minerals; kidney function; bone structure. Results: Some patients needed drug dose adjustments up to 66%. We were able to identify kidney structural and functional changes. We could share those experiences in a multidisciplinary way, contributing significantly to provide more experience to the medical residents. Conclusion: Specialized outpatient treatment is responsible for providing more efficient and safe treatment to the patients, and it is also important to enable further medical research.


hypoparathyroidism; parathyroid hormone; postoperative care; postoperative complications; thyroidectomy.


1. Asari R, Passler C, Kaczirek K, Scheuba C, Niederle B. Hypoparathyroidism after total thyroidectomy: A prospective study. Arch Surg. 2008;143(2):132-7. PMid:18283137.

2. Minuto MN, Reina S, Monti E, Ansaldo GL, Varaldo E. Morbidity following thyroid surgery: acceptable rates and how to manage complicated patients. J Endocrinol Invest. 2019;42(11):1291-7. PMid:31124043.

3. Thomusch O, Machens A, Sekulla C, Ukkat J, Brauckhoff M, Dralle H. The impact of surgical technique on postoperative hypoparathyroidism in bilateral thyroid surgery: a multivariate analysis of 5846 consecutive patients. Surgery. 2003;133(2):180-5. PMid:12605179.

4. Rosato L, Avenia N, Bernante P, De Palma M, Gulino G, Nasi PG, Pelizzo MR, Pezzullo L. Complications of thyroid surgery: analysis of a multicentric study on 14,934 patients operated on in Italy over 5 years. World J Surg. 2004;28(3):271-6. PMid:14961204.

5. Castro A, Oleaga A, Arias PP, Paja M, Carcedo EG, Escolá CÁ. Resumen ejecutivo del documento de consenso SEORL CCC-SEEN sobre hipoparatiroidismo postiroidectomía. Endocrinol Diabetes Nutr. 2019;66(7):459-63.

6. Lopes MP, Kliemann BS, Bini IB, Kulchetscki R, Borsani V, Savi L, Borba VZ, Moreira CA. Hypoparathyroidism and pseudohypoparathyroidism: etiology, laboratory features and complications. Arch Endocrinol Metab. 2016;60(6):532-6. PMid:27901178.

7. Chan FK, Tiu SC, Choi KL, Choi CH, Kong AP, Shek CC. Increased bone mineral density in patients with chronic hypoparathyroidism. J Clin Endocrinol Metab. 2003;88(7):3155-9. PMid:12843159.

8. Stein R, Godel V. Hypocalcemic cataract. J Pediatr Ophthalmol Strabismus. 1980;17(3):159-61. PMid:6993651.

9. Rastogi R, Beauchamp NJ, Ladenson PW. Calcification of the basal ganglia in chronic hypoparathyroidism. J Clin Endocrinol Metab. 2003;88(4):1476-7. PMid:12679425.

10. Kinirons MJ, Glasgow JF. The chronology of dentinal defects related to medical findings in hypoparathyroidism. J Dent. 1985;13(4):346-9. PMid:3866776.

11. Udovcic M, Pena RH, Patham B, Tabatabai L, Kansara A. Hypothyroidism and the Heart. Methodist DeBakey Cardiovasc J. 2017;13(2):55-9. PMid:28740582.

12. Sousa AA, Salles JMP, Soares JMA, Moraes GM, Carvalho JR, Savassi-Rocha PR. Fatores preditores para hipocalcemia pós-tireoidectomia. Rev Col Bras Cir. 2012;39(6):476-82.

13. Araújo Filho VJF, Machado MT, Sondermann A, Carlucci Jr D, Moysés RA, Ferraz AR. Hipocalcemia e hipoparatireoidismo clínico após tireoidectomia total. Rev Col Bras Cir. 2004;31(4):233-5.

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