Archives of Head and Neck Surgery
https://archivesheadnecksurgery.com/article/doi/10.4322/ahns.2020.0002
Archives of Head and Neck Surgery
Case Report Miscellaneous

Extramedullary hematopoiesis of the middle ear

Vanessa Ribeiro Orlando, Marcelo Castro Alves de Sousa, Nicodemos José Alves de Sousa

Downloads: 0
Views: 89

Abstract

Extramedullary hematopoiesis is characterized by the production of blood at sites outside the bone marrow that occurs due to an increased demand of the hematopoietic system as a consequence of chronic anemia associated with ineffective bone marrow response. Theoretically, any organ may be involved in extramedullary hematopoiesis. In this case report, a patient with sickle cell anemia developed an extremely rare presentation of extramedullary hematopoiesis in the middle ear. Therefore, extramedullary hematopoiesis should be included as a differential diagnosis of middle ear masses in patients with chronic anemia.

Keywords

anemia, sickle cell; ear, middle; hematopoiesis; hematopoiesis, extramedullary; hemoglobin sickle cell disease.

References

1. Orphanidou-Vlachou E, Tziakouri-Shiakalli C, Georgiades CS. Extramedullary hemopoiesis. Semin Ultrasound CT MR. 2014;35(3):255-62. http://dx.doi.org/10.1053/j.sult.2013.12.001. PMid:24929265.

2. Huang Y, Liu R, Wei X, Liu J, Pan L, Yang G, Lai Y. Erythropoiesis and iron homeostasis in non-transfusion-dependent thalassemia patients with extramedullary hematopoiesis. Hindawi BioMed Research International. 2019;2019:4504302. https://doi.org/10.1155/2019/4504302.

3. Silva LPA, Nova CV, Lucena R. Sickle cell anemia and hearing loss among children and youngsters: literature review. Braz J Otorhinolaryngol. 2012;78(1):126-31. http://dx.doi.org/10.1590/S1808-86942012000100020. PMid:22392250.

4. Aronsohn MS, Antonelli PJ, Mancuso A. Hematopoiesis presenting as a middle ear mass. Otol Neurotol. 2003;24(6):963-4. http://dx.doi.org/10.1097/00129492-200311000-00027. PMid:14600485.

5. Sohawon D, Lau KK, Lau T, Bowden DK. Extra-medullary haematopoiesis: A pictorial review of its typical and atypical locations. J Med Imaging Radiat Oncol. 2012;56(5):538-44. http://dx.doi.org/10.1111/j.1754-9485.2012.02397.x. PMid:23043573.

5efa30d50e8825d30ac4395c archives Articles
Links & Downloads

Arch. Head Neck Surg.

Share this page
Page Sections