Archives of Head and Neck Surgery
https://archivesheadnecksurgery.com/article/doi/10.4322/ahns.2020.0010
Archives of Head and Neck Surgery
Case Report Miscellaneous

Rosai-Dorfman disease as a differential diagnosis of cervical adenopathy

Victor Giovannino Accetta, Vinícius Campos Oliveira, Sílvia Migueis Picado Petrarolha, Angelo Sementilli, Rogério Aparecido Dedivitis

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Abstract

Introduction: Rosai-Dorfman disease (RDD), also known as sinus histiocytosis with massive lymphadenopathy (SHML), is a rare benign idiopathic disease that affects both nodal and extranodal sites. Case report: A female patient aged 27 years with right side cervical adenopathy of levels IV and V, both mobile, painless and of fibroelastic consistency, with no signs of inflammation was evaluated. Histopathology of the lymph node biopsy showed preserved lymphoid architecture and presence of numerous mature histiocytes compatible with RDD.

Keywords

histiocytosis; emperipolesis; hemophagocytic lymphohistiocytosis.

References

1. Lai KL, Abdullah V, Ng KS, Fung NS, van Hasselt CA. Rosai-Dorfman disease: Presentation, diagnosis, and treatment. Head Neck J Sci Spec. 2013;35(3):85-8. http://dx.doi.org/10.1002/hed.21930. PMid:22083607.

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3. Mar WA, Yu JH, Knuttinen MG, Horowitz JM, David O, Wilbur A, Menias CO. Rosai-Dorfman disease: Manifestations outside of the head and neck. AJR Am J Roentgenol. 2017;208(4):721-32. http://dx.doi.org/10.2214/AJR.15.15504. PMid:28140608.

4. Padoveze EH, Alvarenga ML, Falzoni R, Rabay FMO. Doença de Rosai-Dorfman cutânea: relato de caso e revisão de literatura. Bras Patol Med Lab. 2011;47(1):65-9. http://dx.doi.org/10.1590/S1676-24442011000100009.

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Submitted date:
10/16/2018

Accepted date:
03/26/2020

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