Archives of Head and Neck Surgery
https://archivesheadnecksurgery.com/article/doi/10.4322/ahns.2020.0011
Archives of Head and Neck Surgery
Case Report Head and neck cutaneous tumors

Active surveillance after complete spontaneous regression of a metastatic Merkel cell carcinoma of the head

Alvaro Sanabria, Iván Vega, Lizeth Sánchez

Downloads: 0
Views: 159

Abstract

Complete spontaneous regression (CSR) of Merkel cell carcinoma (MCC) is a known phenomenon. There are no reports of an active decision to avoid resection or adjuvant treatment and keep surveillance after CSR of MCC in the literature. An 84-year-old Caucasian male patient with a 6×5 cm MCC on the left forehead, with evidence of satellite nodules and a lymph node conglomerate in the left parotid region compatible with metastasis and confirmed by 18F-FDG PET-CT, presented CSR of the neoplasm. The use of PET-CT and non-operative active surveillance strategy can assist with monitoring response, thus avoiding unnecessary resections.

Keywords

Merkel cell carcinoma; spontaneous neoplasm regression; active surveillance; 18F-FDG PET-CT

References

1. Han AY, Patel PB, Anderson M, Diaz MFP, Chin R, St. John MA. Adjuvant radiation therapy improves patient survival in early-stage merkel cell carcinoma: a 15-year single-institution study. Laryngoscope. 2018;128(8):1862-6. http://dx.doi.org/10.1002/lary.27031. PMid:29314048.

2. Ahmadi Moghaddam P, Cornejo KM, Hutchinson L, Tomaszewicz K, Dresser K, Deng A, OʼDonnell P. Complete spontaneous regression of merkel cell carcinoma after biopsy: a case report and review of the literature. Am J Dermatopathol. 2016;38(11):e154-8. http://dx.doi.org/10.1097/DAD.0000000000000614. PMid:27759689.

3. Ciudad C, Aviles JA, Alfageme F, Lecona M, Suarez R, Lazaro P. Spontaneous regression in merkel cell carcinoma: report of two cases with a description of dermoscopic features and review of the literature. Dermatol Surg. 2010;36(5):687-93. http://dx.doi.org/10.1111/j.1524-4725.2010.01531.x. PMid:20384741.

4. Connelly TJ, Cribier B, Brown TJ, Yanguas I. Complete spontaneous regression of Merkel cell carcinoma: a review of the 10 reported cases. Dermatol Surg. 2000;26(9):853-6. http://dx.doi.org/10.1046/j.1524-4725.2000.00054.x. PMid:10971559.

5. Richetta AG, Mancini M, Torroni A, Lorè B, Iannetti G, Sardella B, Calvieri S. Total spontaneous regression of advanced merkel cell carcinoma after biopsy: review and a new case. Dermatol Surg. 2008;34(6):815-22. http://dx.doi.org/10.1097/00042728-200806000-00018. PMid:18363731.


Submitted date:
02/26/2020

Accepted date:
05/01/2020

5f3bcc2f0e8825fe15e5db48 archives Articles
Links & Downloads

Arch. Head Neck Surg.

Share this page
Page Sections