Castleman’s disease: atypical pathology – a case report
Daysi Alejandra León Sanguano, Christian Paul Jara Santamaria, Diego Andrés Vasquéz Bracho, David Santiago Álvarez Gahona, Duilio Antonio Palacios Molina
Abstract
Castleman’s disease is a rare, benign pathology characterized by lymph node hyperplasia. Clinically, it is classified as either multicentric or unicentric disease. The choice of treatment depends on the subtype of the disease, with surgical intervention being preferred for unicentric cases and a combination of chemotherapy, corticosteroids, or immunomodulators being used for multicentric cases. Given the rarity of this pathology, the objective of this study is to present a case report of a male patient with an anatomopathological diagnosis of Castleman’s disease.
Keywords
References
1. Ehsan N, Zahra F. Castleman disease [Internet]. Treasure Island: StatPearls Publishing; 2022 [cited 2023 May 24]. Available from: https://www.ncbi.nlm. nih.gov/books/NBK576394/
2. Aguiar Quevedo K, Jordá Aragón C, Mancheño Franch N, Sales Badía G, Calvo Medina V, García Zarza A, Pastor Guillén J. Enfermedad de Castleman: dos variantes, dos pacientes. Rev Patol Respir. 2011;14(4):138-42. http://dx.doi. org/10.1016/S1576-9895(11)70126-6.
3. Masaki Y, Arita K, Sakai T, Takai K, Aoki S, Kawabata H. Castleman disease and TAFRO syndrome. Ann Hematol. 2022;101(3):485-90. http://dx.doi.org/10.1007/ s00277-022-04762-6. PMid:35044513.
4. Krokenberger M, Schwamborn K, Strassen U. Prevalence of Castleman’s disease in patients suffering from cervical lymphadenopathy. Laryngoscope Investig Otolaryngol. 2022;7(5):1430-5. http://dx.doi.org/10.1002/lio2.891. PMid:36258858.
5. Talat N, Belgaumkar AP, Schulte KM. Surgery in Castleman’s disease: a systematic review of 404 published cases. Ann Surg. 2012;255(4):677-84. http://dx.doi. org/10.1097/SLA.0b013e318249dcdc. PMid:22367441.
Submitted date:
06/16/2023
Accepted date:
07/21/2023